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Research Scientist, Genetics Target Discovery
Location:
Oxford, Oxon
Description:
The position We are looking for a Research Scientist to join our Genetics Target Discovery team, to implement cutting:edge human genetics insights to identify and validate drug targets for cardiometabolic and haematological diseases. In this role you will apply your expertise in genetic data analytics and interpretation of human genetics to identify novel targets. Through close collaboration with computational biologists and in vitro scientists, you will combine evidence from multiple sources to identify biological targets and pathways. You will be expected to analyse genetic data, lead projects, and regularly coordinate with interdisciplinary project teams and experts from diverse subject areas as well as external partners. We are particularly interested in hearing from candidates with human genetics knowledge applied in a drug discovery setting. This position will be located in Copenhagen, Denmark or Oxford, UK. Main responsibilities include: :Providing human genetic support to project teams responsible for the identification of novel drug targets.:Working as part of interdisciplinary teams tasked with driving forward novel targets into the pipeline.:Using genetic data with other omics : proteomics, metabolomics, transcriptomics, and epigenetics : to better understand disease biology.:Analysing and interpreting complex genetic and genomic data from multiple sources.:Organising own daily work and make independent decisions related to research activities.:Ensuring all research is conducted in accordance with ethical guidelines and regulations and maintain accurate and complete records of all findings and methodologies.:Effective communication of complex scientific ideas and data to a variety of audiences. The Human Genetics Centre of Excellence (CoE) is part of a collaborative endeavour where you will work alongside statistical geneticists, clinicians, and computational and laboratory scientists from across the organisation, and with external collaborators, to help get the right treatment to the right patient. We welcome candidates with a good team ethic, who pay close attention to detail, enjoy a fast paced, dynamic environment where creative intellectual independence and knowledge sharing is actively encouraged. Most importantly, you must have a strong interest in applying your skills in the field of drug development. Qualifications A successful candidate holds a Ph.D. in human genetics, statistical genetics, genetic epidemiology, or other related fields. They will have experience with approaches for variant:trait and gene:trait association (including GWAS, PheWAS, TWAS, QTL mapping, Mendelian randomization, familial genetic studies). Previous experience in handling omics data (e.g. transcriptomics, proteomics) would be considered an advantage. You will show experience and knowledge of: :Data:driven methods to identify and characterise genetic associations with disease.:Communicating insights and presenting concepts to a diverse audience. :Understanding of cardiometabolic and/or haematological diseases e.g. obesity, diabetes, and cardiovascular disease.:Working in high performance computing environment using tools such as R and Python.:Human genetics applied in a drug discovery setting. On a personal level, we are hoping to welcome candidate who is an enthusiastic team player, able to motivate other colleagues and drive processes. Someone, who is self:driven, with business mindset, diligently reaching goals in constructive collaboration with colleagues and external stakeholders, and able to communicate the research outcome to different audiences. About the department You will be a member of our Genetics Target Discovery team led by Ciara Vangjeli, which is part of the Human Genetics CoE led by Vice President, Joanna Howson. The focus of the CoE is to use data science and human genetics to disco
Posted:
April 1 on Tip Top Job
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More About this Listing: Research Scientist, Genetics Target Discovery
Research Scientist, Genetics Target Discovery is a Research Research Scientist Job located in Oxford OXF. Find other listings like Research Scientist, Genetics Target Discovery by searching Oodle for Research Research Scientist Jobs.
Research Scientist, Genetics Target Discovery is a Research Research Scientist Job located in Oxford OXF. Find other listings like Research Scientist, Genetics Target Discovery by searching Oodle for Research Research Scientist Jobs.